Install antivirus software
A good virus scanner is must-have protection. Three good free virus scanners are Antivir, Avast, and AVG. If you want broader coverage or perks like tech support, any of the Top Windows Antivirus should suffice.
Install a firewall
My pick for desktop firewalls is the free ZoneAlarm Personal Firewall which offers permission-based protection for both inbound and outbound Internet traffic. Or enable the built-in Windows firewall unless you've opted for an Internet security suite.
Keep up-to-date on patches
Visiting Windows Update monthly is a must, but other third-party software may be (and often is) vulnerable to exploit as well. Be sure to visit Secunia Security Advisor monthly as well. It's free, too, but the aggravation it can save you is priceless.
Beef up wireless security
If you're planning on going the laptop route, chances are you'll be connecting via wireless hotspots at least some o f the time. For security tips specific to hotspot safety, see: "Using Your Laptop at Starbucks, Is it Safe?".
Consider physical security
Christopher Null from YahooTech has an excellent set of suggestions for physically securing your laptop and other mobile devices from theft. See "Mobile Gear Security Advice For Students" for details.
Keep abreast of Internet scams
Social engineering attacks are on the rise. One gullible slip and not only can your computer be infected, your personal financial security might also be compromised. Up your savvy by familiarizing yourself with the "Top Email and Internet Scams". (You just might want to share this link with your parents).
Don't share your USB drives
When it comes to viruses, USB drives are the floppy disks of the 90s. Don't loan your thumb drive to others and try to avoid letting them stick their thumb drive in your computer. If you simply must share, disable autorun before inserting the USB drive and then scan the drive with antivirus before transferring any files.
Don't roll your eyes
If you're rolling your eyes thinking all of this talk about computer security is just middle-aged paranoia, think again. But don't let me tell you. Listen to the wisdom of one of your peers, Jeffrey Elkus of the University of Cinncinnati says it far better than I. See: "Elkus, Fight the Deadly Viruses" for details on why you too are a target of attackers.
Also see:
Buyer's Guide: Back to School PCs Great Stuff for Your PC Gifts for Geeks and Gamers (Hey, you've gotta have some fun!)

